The Zanzibar University Students Organization (ZANUSO) is concerned with the students' academic, political, social and recreational activities. The University, through the Dean of the Students, encourages the students to form academic and professional associations. At present all these association are under the umbrella of ZANUSO.

With several others being under construction, some of the existing professional associations include: -

• Zanzibar University Law Society (ZULAS);
• Zanzibar University Accounting & Finance Association (ZUAFA);
• Zanzibar University Marketing Association (ZUMA);
• Zanzibar University English Speaker's Society (ZUESS);
• Zanzibar University Bachelor of Arts Students Association (ZUBASA);
• Zanzibar University Students HIV/AIDS Club (ZUSHAC);
• Zanzibar University Voluntary Environment Students Organization (ZUVESO);
• Zanzibar University Economic Association (ZUECA);
• Zanzibar University Business Information Technology Association (ZUBITA);
• Zanzibar University Engineering Students' Association (ZUESA);
• Zanzibar University Social Work Students (ZUSOWS);
• Zanzibar University Health Students' Association (ZUHSA).

However students' activities are subjected to the following rules:

• Total commitment in all aspects of students' activities whether in planning, preparations or execution of the general education policy in the University in particular and in Zanzibar in general.
• Providing all University students – males and females – with opportunity to participate in accordance with the general regulations of the University and the Students Affairs Department.